Test-Retest-Reliability of Computer-Based Metamorphopsia Measurement in Macular Diseases.

Area of Science:

• Ophthalmology
• Medical Technology
• Visual Science

Background:

• Metamorphopsia, a visual distortion, is a common symptom in various macular diseases.
• Accurate and reliable measurement of metamorphopsia is crucial for patient management and clinical trials.
• Existing methods for metamorphopsia assessment may have limitations in terms of precision and repeatability.

Purpose of the Study:

• To determine the test-retest reliability of metamorphopsia measurements using a computer-based method.
• To evaluate the repeatability of metamorphopsia amplitude, position, and area quantification.
• To assess the reliability of the AMD - A Metamorphopsia Detector software in patients with diverse maculopathies.

Main Methods:

• Test-retest reliability was assessed in 36 eyes of patients diagnosed with macular diseases.
• Metamorphopsia parameters (amplitude, position, area) were measured using the AMD - A Metamorphopsia Detector software.
• The intraclass correlation coefficient (ICC) was calculated to quantify measurement repeatability.

Main Results:

• Metamorphopsia measurements using the AMD - A Metamorphopsia Detector software showed high reliability and repeatability.
• The ICC values for all measured indices were excellent, ranging from 0.95 to 0.97.
• The software demonstrated consistent results across repeated measurements in patients with maculopathies.

Conclusions:

• The computer-based metamorphopsia measurement using AMD - A Metamorphopsia Detector software is a highly reliable and repeatable method.
• This tool serves as a valuable supplement for visual function testing in clinical practice and research settings.
• The findings support the use of this technology for monitoring disease progression and treatment efficacy in patients with macular diseases.