Treating pediatric colorectal patients in low and middle income settings: Creative adaptation to the resources

Giulia Brisighelli1, Victor Etwire2, Taiwo Lawal3

  • 1Department of Pediatric Surgery, Pediatric Colorectal and Pelvic Reconstruction Centre, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, 7 York Road, Parktown, 2193 Johannesburg, South Africa.

Insights

Pediatric colorectal diseases in low- and middle-income countries present late and with complications. Infectious diseases and trauma significantly impact treatment, necessitating adapted approaches for better outcomes.

Area of Science:

  • Pediatric surgery
  • Colorectal surgery
  • Global health

Background:

  • Colorectal disease in children in low- and middle-income countries (LMIC) often presents late, leading to increased complications and limited follow-up.
  • Infectious diseases like tuberculosis (TB), human immunodeficiency virus (HIV), and human papilloma virus (HPV) are prevalent and complicate primary colorectal conditions.
  • Perineal trauma from various causes and endemic conditions present unique challenges in LMIC settings.

Purpose of the Study:

  • To discuss the unique profiles of pediatric colorectal diseases in LMIC.
  • To highlight the impact of infectious diseases and trauma on colorectal care.
  • To explore adaptations needed for resource-poor healthcare settings.

Main Methods:

  • Review of existing literature and clinical observations on pediatric colorectal diseases in LMIC.
  • Discussion of specific endemic conditions and their management challenges.
  • Analysis of the impact of socioeconomic factors on colorectal care.

Main Results:

  • Late presentation and complications are characteristic of pediatric colorectal diseases in LMIC.
  • Infectious agents (TB, HIV, HPV) and perineal trauma significantly affect wound healing and surgical outcomes.
  • Unique conditions like congenital pouch colon and H-type rectal fistulae require specialized management.

Conclusions:

  • Pediatric colorectal care in LMIC requires creative adaptations due to unique disease profiles and resource limitations.
  • Addressing socioeconomic factors and endemic conditions is crucial for optimizing treatment.
  • Further research is needed to understand and manage specific endemic colorectal diseases in LMIC.

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