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Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
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Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
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Reply: MELAS can be delineated from CADASIL by genotype and phenotype

Nai-Yi Liao1, Kwong-Kum Liao2, Yi-Chu Liao3

  • 1Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan.

Neurobiology of Aging
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PubMed
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No abstract available in PubMed .

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