Central serous chorioretinopathy imaging biomarkers
Sumit Randhir Singh1, Claudio Iovino2, Dinah Zur3
1Jacobs Retina Center, University of California San Diego, La Jolla, California, USA.
The British Journal of Ophthalmology
|December 8, 2020
Summary
Central serous chorioretinopathy (CSCR) visual outcomes are predicted by changes in central macular thickness and subretinal fluid height. Disease resolution correlates with changes in central macular thickness and subfoveal choroidal thickness.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Medical Imaging
Background:
- Central serous chorioretinopathy (CSCR) is a condition affecting vision.
- Understanding predictive factors for CSCR outcomes is crucial for patient management.
Purpose of the Study:
- To identify predictors of visual and anatomical outcomes in CSCR over 12 months.
- To correlate optical coherence tomography (OCT) findings with disease progression and visual acuity.
Main Methods:
- Retrospective analysis of 231 eyes with acute or chronic CSCR.
- Inclusion of demographic, systemic, and OCT parameters (CMT, SFCT, EZ damage) as predictors.
- Regression analysis to assess visual acuity (BCVA) and disease resolution.
Main Results:
- Significant changes observed in BCVA, CMT, subretinal fluid height, and SFCT over 12 months.
- Baseline CMT and SRF height predicted good visual outcomes.
- Changes in CMT and SFCT correlated with disease resolution.
Conclusions:
- OCT parameters, including CMT and SFCT changes, predict CSCR resolution.
- Changes in CMT and baseline SRF height correlate with BCVA changes over 12 months.
