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Published on: May 23, 2025
On the rate coding response of peripheral sensory neurons
1Department of Electrical and Computer Engineering and Institute of Biomedical Engineering, University of Toronto, Toronto, M5S3G4, Canada. willy.wong@utoronto.ca.
Abstract:
The rate coding response of a single peripheral sensory neuron in the asymptotic, near-equilibrium limit can be derived using information theory, asymptotic Bayesian statistics and a theory of complex systems. Almost no biological knowledge is required. The theoretical expression shows good agreement with spike-frequency adaptation data across different sensory modalities and animal species. The approach permits the discovery of a new neurophysiological equation and shares similarities with statistical physics.
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