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Frequency of Contact Lens Complications Between Contact Lens Wearers Using Multipurpose Solutions Versus Hydrogen
Anna A Tichenor1, Stacey S Cofield, Drew Gann
1Indiana University (A.A.T.), School of Optometry, Bloomington, IN; University of Alabama at Birmingham School of Optometry (S.S.C., J.J.N.), Birmingham, AL; EyeCare Associates (D.G.), Hueytown, Alabama; Centre for Ocular Research and Education (CORE) (M.E., A.N., K.W., L.W.J.), School of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada ; and Centre for Eye and Vision Research (LWJ), Hong Kong.
Objectives:
To retrospectively compare frequency of contact lens (CL) complications in soft CL users of hydrogen peroxide (H2O2) and multipurpose solutions (MPS).
Methods:
This was a multicenter, retrospective chart review of CL records from each patient's three most recent eye examinations at academic and private practices. Patients must have used the same solution type for at least 3 years. Univariate analyses were conducted using t tests, and chi-square or Fisher's exact test for categorical measures.
Results:
There were 1,137 patients included, with 670 (59%) using MPS and 467 (41%) H2O2. In total, 706 (62%) experienced at least one complication; 409 used MPS and 297 used H2O2. There was no difference in the proportion of patients experiencing at least one complication between MPS (61%) and H2O2 (64%) (P=0.38). Multipurpose solutions users were more likely to report discomfort compared with H2O2 users (P=0.04). Presumed microbial keratitis was experienced by 16 MPS and nine H2O2 users (P=0.60).
Conclusions:
No significant differences were found in the frequency of CL complications between MPS and H2O2. H2O2 users were less likely to report discomfort and thus switching to a H2O2 system may be an alternative in CL users with discomfort.
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