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[New antihypertensive therapy in diabetics]
Diabete & Metabolisme
|November 1, 1987
Summary
High blood pressure in diabetic patients, especially insulin-dependent, requires careful management. Antihypertensive treatments, particularly calcium antagonists and ACE inhibitors, are effective in reducing complications like retinopathy and nephropathy.
Area of Science:
- Endocrinology
- Cardiology
- Nephrology
Context:
- Arterial hypertension affects approximately one-third of diabetic patients.
- WHO criteria for hypertension may not be suitable for insulin-dependent diabetics.
- Elevated blood pressure exacerbates diabetic angiopathy.
Purpose:
- To review the impact of arterial hypertension on diabetic complications.
- To evaluate the efficacy of antihypertensive treatments in diabetic patients.
Summary:
- Slight increases in blood pressure significantly worsen diabetic angiopathy, retinopathy, and nephropathy.
- Antihypertensive treatment is crucial for reducing albumin excretion and preventing clinical diabetic nephropathy.
- Calcium antagonists and angiotensin-converting enzyme inhibitors are recommended for hypertensive diabetics due to efficacy and tolerability.
Impact:
- Effective blood pressure control can prevent or delay diabetic microvascular complications.
- Specific antihypertensive drugs offer benefits beyond blood pressure reduction, improving organ-specific hemodynamics.
- This review highlights the importance of tailored antihypertensive strategies in managing diabetes.