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Updated: Nov 26, 2025

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
Published on: April 26, 2012
[Really Just a Side Effect of Capecitabine? Case Report from the Oncological and Neurological Consultation]
Katrin Schmutz-Kober1, Liliane Kappeler1
1Onkologische und neurologische Sprechstunde, Bürgerspital Solothurn.
Abstract:
Really Just a Side Effect of Capecitabine? Case Report from the Oncological and Neurological Consultation Abstract. A case of our oncology and neurology department is presented. A male patient developed sensory polyneuropathy and mild left-side hemiparesis while receiving neoadjuvant radiochemotherapy with capecitabine as treatment for rectal cancer. Polyneuropathy as a side effect of capecitabine was thought to be the culprit. But upper motor neuron signs were highly supposed to be caused by an acute varicella zoster myelitis, a rare complication of varicella zoster infection possibly facilitated by immunosuppression due to chemotherapy.
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