Association between endometriosis and increased arterial stiffness

Area of Science:

• Gynecology
• Cardiology
• Inflammation Research

Background:

• Endometriosis is a common gynecologic condition linked to systemic inflammation and atherogenic factors.
• These factors suggest a potential for increased cardiovascular risk in women with endometriosis.

Purpose of the Study:

• To evaluate arterial stiffness using the cardio-ankle vascular index (CAVI) in women diagnosed with endometriosis compared to controls.
• To determine if endometriosis is associated with subclinical arterial changes.

Main Methods:

• A cohort of 44 women with endometriosis and 76 age-matched controls were assessed.
• Arterial stiffness was measured using cardio-ankle vascular index (CAVI).
• Histopathologic examination or MRI confirmed endometriosis diagnosis.

Main Results:

• Women with endometriosis exhibited significantly higher CAVI values, indicating increased arterial stiffness.
• Elevated C-reactive protein levels were noted in the endometriosis group, suggesting higher inflammation.
• No significant differences in age, BMI, waist circumference, or blood pressure were found between groups.

Conclusions:

• Endometriosis is associated with increased arterial stiffness as measured by CAVI.
• Clinicians should recognize the potential for elevated cardiovascular risk in women with endometriosis.