Pseudomyxoma pleurii: unusual location of a rare disease

Area of Science:

• Oncology
• Radiology
• Pathology

Background:

• Pseudomyxoma peritonei (PMP) is a rare condition characterized by mucinous ascites.
• Pleural extension of PMP is exceptionally rare, with dissemination occurring via transdiaphragmatic or hematogenous routes.
• Appendiceal and ovarian mucinous tumors are the most common primary sources.

Observation:

• This report details a rare case of PMP with pleural involvement in a 55-year-old female.
• The patient had a history of surgery for ovarian mucinous adenocarcinoma.
• The presentation included subpleural nodular thickening alongside PMP.

Findings:

• Imaging is crucial for diagnosing PMP with pleural extension.
• Histological confirmation remains the gold standard for diagnosis.
• Subpleural nodular thickening is a significant imaging finding suggestive of this condition.

Implications:

• Early recognition of PMP with pleural extension is vital for patient management.
• Radiological findings, particularly subpleural thickening, should prompt consideration of PMP.
• This case highlights the importance of a multidisciplinary approach in diagnosing and managing rare oncological presentations.