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Published on: September 11, 2020
Emergence of Meningitis Caused by Nonvaccine Serotypes of Pneumococcus in Rural United States
Jessie Marks1, Guru V Bhoojhawon1, Katherine D Patrick1
1Stead Family Department of Pediatrics, University of Iowa Stead Family Children's Hospital, 200 Hawkins Dr., Iowa City, Iowa 52242, USA.
Abstract:
Pneumococcal conjugate vaccines have decreased the rates of invasive pneumococcal disease (IPD) in children. Since vaccine introduction, however, rates of infection due to nonvaccine Streptococcus pneumoniae serotypes have increased. We now describe 3 meningitis cases due to the nonvaccine serotypes 35B and 11A from rural United States.
Insights
Pneumococcal conjugate vaccines reduced invasive pneumococcal disease (IPD) in children. However, infections from nonvaccine Streptococcus pneumoniae serotypes, like 35B and 11A causing meningitis, have increased.
Area of Science:
- Microbiology
- Epidemiology
- Vaccinology
Background:
- Pneumococcal conjugate vaccines (PCVs) have significantly reduced invasive pneumococcal disease (IPD) in children.
- Post-vaccine introduction, a rise in infections caused by nonvaccine Streptococcus pneumoniae serotypes has been observed.
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