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SCUBE1 Controls BMPR2-Relevant Pulmonary Endothelial Function: Implications for Diagnostic Marker Development in

Wei Sun1, Ying Tang1, Yi-Yin Tai1

  • 1Center for Pulmonary Vascular Biology and Medicine, Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, Division of Cardiology and Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

JACC. Basic to Translational Science
|December 9, 2020
PubMed
Abstract

Keywords:
BMP, bone morphogenetic proteinBMPR2EC, endothelial cellPAEC, pulmonary arterial endothelial cellPAH, pulmonary arterial hypertensionPAP, pulmonary artery pressurePCWP, pulmonary capillary wedge pressurePH, pulmonary hypertensionPVR, pulmonary vascular resistanceRV, right ventricleSCUBE1WSPH, World Symposium on Pulmonary HypertensionendotheliumiPSC-EC, induced pluripotent stem cell-endothelial cellmPAP, mean pulmonary artery pressurepulmonary hypertension

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