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Updated: Nov 26, 2025

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The relation between regular outpatient follow-up and frequency of emergency department visits in sickle cell
Abeer F Ismail1, Raghad A Tarawah, Zainab Y Azzouni
1Department of Pediatrics, Taibah University, Al Madinah Al Munawarah, Kingdom of Saudi Arabia. E-mail. abeerfathy2000@yahoo.com.
Insights
Regular outpatient department (OPD) follow-up is crucial for managing pediatric sickle cell disease (SCD). Missing OPD appointments significantly increases emergency department (ED) visits, highlighting the need for consistent patient engagement in SCD care.
Area of Science:
- Pediatric Hematology
- Public Health
Background:
- Sickle Cell Disease (SCD) is a genetic blood disorder requiring consistent medical management.
- Pediatric patients with SCD often face challenges in accessing regular healthcare, leading to potential complications.
Purpose of the Study:
- To investigate the association between emergency department (ED) visit frequency and outpatient department (OPD) follow-up adherence in pediatric SCD patients.
- To identify factors influencing ED utilization among children with SCD.
Main Methods:
- A retrospective cohort study analyzed data from 247 pediatric SCD patients over a three-year period (2016-2018) in Saudi Arabia.
- Electronic medical records were used to extract demographic data, medication information, and frequencies of ED and OPD visits.
- Statistical analyses included Pearson correlation, linear regression, and independent sample t-tests.
Main Results:
- No significant correlation was found between the overall frequency of ED visits and regular OPD visits.
- A significant positive correlation was identified between ED visits and missed OPD appointments.
- Each missed OPD appointment was associated with approximately 1.92 ED visits, indicating a high reliance on emergency care (43%).
Conclusions:
- Regular OPD follow-up is essential for effective management of pediatric SCD.
- Missed OPD appointments are a key predictor of increased ED utilization in this population.
- Strategies to improve OPD adherence may reduce ED visits and enhance overall SCD patient care.
Objective:
To evaluate the relationship between the frequency of ED visits and outpatient department (OPD) follow-up in sickle cell disease (SCD) pediatric patients.
Methods:
A retrospective cohort study included 247 SCD pediatric patients between January 2016 and December 2018 at the Maternity and Children Hospital, Department of Pediatrics, Al Medinah Al Munawarah, Saudi Arabia. Data were extracted from electronic medical record system; patient demographics, medications, frequency of emergency department (ED) and OPD visits. Pearson correlation coefficient, linear regression and independent sample t-test were applied.
Results:
There was no significant correlation (95% CI [-0.013- 0.233]; p=0.07) between the frequency of ED and OPD visits. However, a significant correlation was found between ED visits and missed OPD appointments. Thus, linear regression was applied and indicated that one missed OPD appointment is associated with 1.92 ED visits, (95% CI: 0.19-0.42; p less than 0.001). Also, a higher rate of ED visits was observed when compared with other studies, with a high ED reliance of 43%.
Conclusion:
This study found that regular OPD visits could improve SCD management, as a directly proportional relationship between the frequency of ED visits and missed OPD appointments along with high ED reliance.
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