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Published on: June 12, 2021
[Impact of COVID-19 pandemic on structural heart interventions in Italy]
Giuseppe Tarantini, Luca Nai Fovino, Andrea Scotti1
1Dipartimento di Scienze Cardio-Toraco-Vascolari e Sanità Pubblica, Università degli Studi, Padova.
Insights
The COVID-19 pandemic caused a 79% reduction in structural heart interventions (SHI) in Italy. Procedures like patent foramen ovale closure saw greater declines than transcatheter aortic valve replacement.
Area of Science:
- Cardiology
- Interventional Cardiology
- Public Health
Background:
- The COVID-19 pandemic led to widespread deferral of non-urgent medical procedures globally.
- Healthcare systems worldwide experienced significant disruptions affecting patient care pathways.
Purpose of the Study:
- To quantify the impact of the COVID-19 pandemic on interventional treatments for structural heart disease (SHD) in Italy.
- To analyze changes in the volume of specific SHD procedures during the pandemic lockdown.
Main Methods:
- A nationwide analysis compared structural heart interventions (SHI) during a 4-week lockdown period in 2020 with the same period in 2019.
- Procedures analyzed included transcatheter aortic valve replacement (TAVR), percutaneous mitral valve repair (PMVR), left atrial appendage occlusion (LAAO), and patent foramen ovale (PFO) closure.
- Incidence rate reductions (IRR) were calculated using zero-inflated negative binomial regression.
Main Results:
- Overall SHI volume in Italy decreased by 79% during the lockdown compared to the previous year (IRR 0.21).
- Reductions were more pronounced for PFO closure (IRR 0.03), LAAO (IRR 0.11), and PMVR (IRR 0.12) compared to TAVR (IRR 0.31).
Conclusions:
- The COVID-19 pandemic resulted in a substantial 79% decrease in SHI procedures in Italy.
- Specific procedures like PFO closure, LAAO, and PMVR experienced more significant declines than TAVR.
- Further research is necessary to understand the long-term clinical outcomes for patients with SHD affected by these procedural reductions.
Background:
The coronavirus disease 2019 (COVID-19) pandemic has led to deferral of many non-urgent procedures in most healthcare systems worldwide. With this study we aimed to quantify the impact of COVID-19 on interventional treatment of structural heart disease (SHD) in Italy.
Methods:
Numbers of transfemoral transcatheter aortic valve replacement (TAVR), percutaneous mitral valve repair (PMVR), left atrial appendage occlusion (LAAO), patent foramen ovale (PFO) closures performed over a 4-week period during the national lockdown in Italian centers performing over 60 structural heart interventions (SHI)/year were compared with the same 4-week period in 2019. Incidence rate reductions (IRR) were estimated by zero-inflated negative binomial regression.
Results:
According to our nationwide analysis, SHIs were reduced by 79% as compared to the same period in 2019 (IRR 0.21, 95% confidence interval [CI] 0.15-0.29). This reduction was more substantial for PFO closure (IRR 0.03, 95% CI 0.01-0.07), LAAO (IRR 0.11, 95% CI 0.05-0.25) and PMVR (IRR 0.12, 95% CI 0.04-0.36) as compared to TAVR (IRR 0.31, 95% CI 0.22-0.47).
Conclusions:
The COVID-19 pandemic caused a 79% drop in SHI volumes in Italy. PFO closure, LAAO and PMVR decreased more significantly as compared to TAVR. Further studies are needed to evaluate the impact of this reduction on outcomes of patients with SHD.
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