Gestational Outcomes of Pregnant Women with Unilateral Congenital Renal Agenesis

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Erdem Fadiloglu1, Onur Can Zaim1, Murat Cagan1

  • 1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Fetal and Pediatric Pathology
|December 9, 2020
PubMed

ObjectiveWe evaluated if there were more adverse gestational outcomes of pregnant women with unilateral congenital renal agenesis (UCRA). Study design: This single center retrospective case-control study compared maternal complications and neonatal outcomes from 25 women with UCRA to the outcomes of 125 women with two kidneys. Results: UCRA women had lower gestational weeks at birth and higher rates of preterm delivery (p = 0.004 and <0.001; respectively). Mothers had higher rates of preeclampsia and newborns with congenital anomalies and neonatal intensive care unit (NICU) admission (p = 0.009, 0.042, and 0.039; respectively). Unadjusted odds ratios were significantly higher for preterm delivery and for any APGAR score of <7 at the first 10 min and preeclampsia [OR (95% CI):13.5 (4.66-39.05), 31 (3.44-279.32) and 5.76 (1.33-24.84), respectively]. Conclusion: Maternal UCRA is a risk factor for less optimal obstetric and neonatal outcomes.

Keywords:
congenital anomalyperinatal morbiditypreeclampsiapreterm birthunilateral congenital renal agenesis

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