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Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction
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Intense Pulse Light for Treating Post-LASIK Refractory Dry Eye.

Emmanuel Eric Pazo1, He Huang1, Qingxia Fan1

  • 1He Eye Specialist Hospital, Shenyang, China.

Photobiomodulation, Photomedicine, and Laser Surgery
|December 9, 2020
PubMed
Summary

Optimal Pulse Light (OPT-IPL) treatment effectively manages refractory dry eye (DE) after LASIK surgery. This therapy significantly improves tear film stability and reduces DE symptoms, decreasing the need for artificial tears.

Keywords:
IPLLASIKOSDIdry eyemeibomian gland

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Area of Science:

  • Ophthalmology
  • Medical Technology

Background:

  • Dry eye disease (DE) is a prevalent condition causing ocular discomfort and reduced quality of life.
  • Post-LASIK patients can develop refractory DE unresponsive to conventional treatments.

Purpose of the Study:

  • To evaluate the efficacy and safety of Optimal Pulse Technology-Intense Pulse Light (OPT-IPL) for treating refractory dry eye (DE) in patients who have undergone LASIK.
  • To assess the impact of OPT-IPL on visual acuity, ocular surface disease index (OSDI), tear film stability, and meibomian gland function.

Main Methods:

  • A prospective study involving 36 patients (72 eyes) with post-LASIK refractory DE.
  • The treatment group (42 eyes) received two OPT-IPL sessions, while the control group (30 eyes) received no treatment.
  • Key metrics including noninvasive tear breakup time (NITBUT), OSDI, tear film lipid layer (TFLL) quality, and meibomian gland (MG) function were assessed.

Main Results:

  • OPT-IPL treatment led to significant improvements in NITBUT at 14 and 28 days post-treatment (p < 0.001).
  • Improvements were observed in OSDI, TFLL quality, and MG function at 28 days (p < 0.05).
  • No significant changes were noted in best-corrected visual acuity (BCVA), endothelial cell count (ECC), or intraocular pressure (IOP).

Conclusions:

  • OPT-IPL is a safe and effective treatment for refractory dry eye following LASIK surgery.
  • The treatment reduces DE symptom severity and enhances tear film stability.
  • Reduced artificial tear usage correlates with improved OSDI scores and better TFLL and tear film stability.