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Assessment of Vascular Function in Patients With Chronic Kidney Disease
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Risk Factors for Chronic Kidney Disease in Newly Diagnosed Hypertensive Subjects in Southeast Nigeria

E C Obi1, I I Chukwuonye1, E N Anyabolu2

  • 1Division of Nephrology, Department of Internal Medicine, Federal Medical Centre, Umuahia, Abia State. Nigeria.

West African Journal of Medicine
|December 9, 2020
PubMed

Insights

Newly diagnosed hypertension significantly increases the risk of chronic kidney disease (CKD). Factors like sex, serum uric acid, and triglycerides are associated with CKD in hypertensive patients.

Area of Science:

  • Nephrology
  • Cardiology
  • Public Health

Background:

  • Chronic kidney disease (CKD) is a significant public health concern.
  • Hypertension is a major risk factor for CKD.
  • Understanding CKD prevalence in newly diagnosed hypertensive patients is crucial for early intervention.

Purpose of the Study:

  • To determine the prevalence of CKD in newly diagnosed hypertensive patients.
  • To identify associated risk factors for CKD in this population.

Main Methods:

  • A cross-sectional analytical study was conducted.
  • 120 newly diagnosed hypertensive patients and 120 non-hypertensive controls were recruited.
  • Data on socio-demographics, anthropometrics, and biochemical markers were collected via questionnaires and analyzed.

Main Results:

  • The prevalence of CKD was significantly higher in hypertensive patients (35.0%) compared to controls (9.2%).
  • In hypertensive patients, CKD was associated with sex, serum triglycerides, and serum uric acid.
  • In the control group, CKD was associated with sex, serum total cholesterol, and serum uric acid.

Conclusions:

  • The prevalence of CKD is high among newly diagnosed hypertensive individuals in southeast Nigeria.
  • Sex, serum uric acid, and serum triglyceride levels are associated with CKD in this group.
  • Early screening and management of CKD in hypertensive patients are recommended.
Abstract

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