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Antitumor Drugs and Their Targets
1Molecular Genetics Laboratory, Department of Oral Biology, Faculty of Dentistry, University of Oslo, 0316 Oslo, Norway.
Molecules (Basel, Switzerland)
|December 10, 2020
Summary
Advancements in cancer therapy, including immunotherapy, offer personalized treatments for solid tumors. Evaluating these options is crucial for managing cancer as a chronic disease.
Area of Science:
- Oncology
- Immunology
- Genetics
Background:
- Solid cancer therapy has advanced through innovative basic and clinical research.
- Recent breakthroughs include immune checkpoint inhibitors, vaccines, small drugs, and CAR-T cell therapies.
- Genomic, transcriptomic, and proteomic advancements accelerate cancer research.
Purpose of the Study:
- To review the current therapeutic arsenal against solid cancers.
- To focus on the role and advancements of immunotherapies in cancer treatment.
- To highlight the importance of personalized therapy selection for cancer patients.
Main Methods:
- Review of current literature on solid cancer therapies.
- Focus on immunotherapeutic strategies and their mechanisms.
- Analysis of advancements in cancer genomics and proteomics.
Main Results:
- Novel therapies like biologics, vaccines, and cell therapies are transforming cancer treatment.
- Personalized medicine is becoming a reality, requiring careful evaluation of therapeutic options.
- Understanding cancer hallmarks guides targeted therapeutic strategies.
Conclusions:
- Immunotherapies represent a significant paradigm shift in solid cancer treatment.
- The complexity of cancer necessitates a personalized approach to therapy selection.
- The goal is to manage solid cancers as chronic conditions rather than terminal diseases.
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