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ped_draw: pedigree drawing with ease.

Matt Velinder1, Dillon Lee2, Gabor Marth2

  • 1Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, USA. matt.velinder@utah.edu.

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|December 10, 2020
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Summary
This summary is machine-generated.

Pedigree files, crucial for genetics studies, are hard to visualize. Ped_draw offers a simple solution for creating intuitive visual pedigrees from text files, aiding geneticists and bioinformaticians.

Keywords:
DrawingFamilyFamily studiesGenerationGeneticsInheritanceMendelianPedPedigreeVisualization

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Area of Science:

  • Bioinformatics
  • Genetics
  • Computational Biology

Background:

  • Pedigree files are essential in bioinformatics and genetics for representing sample relatedness, sex, and affected status.
  • Text-based pedigree files are computationally efficient but lack intuitive visual representation of complex family structures and generational data.
  • Visualizing pedigrees enhances interpretability, allowing for easier recognition of patterns and family relationships.

Purpose of the Study:

  • To develop a user-friendly tool for visualizing pedigree data.
  • To address the difficulty of quickly and accurately visualizing pedigrees from standard text files.
  • To provide an accessible solution for researchers needing to interpret family structures.

Main Methods:

  • Introduction of ped_draw, a command-line and web-based tool for pedigree visualization.
  • Utilizes Graphviz for image generation via a simple command-line interface.
  • Web tool offers multiple input methods: pasting, typing, or uploading pedigree files.

Main Results:

  • Ped_draw effectively visualizes complex, multi-generational pedigrees according to established standards.
  • The tool provides a straightforward one-liner command for generating image files.
  • The web interface supports various file input methods and allows saving images in multiple formats.

Conclusions:

  • Ped_draw is a valuable tool that enhances current methods for pedigree visualization through its ease of use.
  • The tool democratizes pedigree visualization, making it accessible to users of all expertise levels.
  • Facilitates quicker and more accurate interpretation of family structures from pedigree data.