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Impaired motor performance in adolescents with esophageal atresia

Unn Inger Moinichen1, Audun Mikkelsen2, Anne Faugli1

  • 1Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Postbox 4950 Nydalen, 0424 Oslo, Norway.

Journal of Pediatric Surgery
|December 10, 2020
PubMed

Insights

Motor development in patients with esophageal atresia (EA) initially normal, but significantly declined by adolescence. Early and ongoing monitoring for motor impairments is crucial for these children.

Area of Science:

  • Pediatric Medicine
  • Developmental Pediatrics
  • Surgical Outcomes

Background:

  • Esophageal atresia (EA) is a congenital condition requiring surgical intervention.
  • Long-term neurodevelopmental outcomes, particularly motor function, in EA patients are not fully understood.
  • Assessing motor development trajectory from infancy to adolescence is critical for comprehensive patient care.

Purpose of the Study:

  • To prospectively evaluate the motor development trajectory in patients with esophageal atresia (EA) from infancy through adolescence.
  • To identify potential associations between clinical factors and motor development outcomes in EA patients.
  • To establish the need for specialized follow-up programs for motor function in EA survivors.

Main Methods:

  • Prospective cohort study of 23 patients with EA.
  • Motor performance assessed at one year using the Psychomotor Developmental Index (PDI) of the Bayley Scales of Infant Development, Second Edition (BSID-II).
  • Adolescent motor function evaluated using the Motor Assessment Battery for Children, Second Edition (MABC-2).

Main Results:

  • Infant motor scores (PDI) were within the normal range (median z-score: -0.006).
  • Adolescent motor scores (MABC-2) were significantly impaired compared to reference values (median z-score: -0.43, p=0.03).
  • Patients with impaired adolescent motor function required significantly more rethoracotomies (p=0.037).

Conclusions:

  • Motor function in patients with esophageal atresia deteriorates from normal in infancy to significantly impaired in adolescence.
  • Interdisciplinary follow-up programs are essential for early detection and management of motor impairments in EA patients.
  • Close monitoring of motor development throughout childhood and adolescence is recommended for EA survivors.
Abstract

Keywords:
Esophageal atresiaMotor developmentMotor skills

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