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Surgical versus Non-Surgical Management of Obstructive Sleep-disordered Breathing in Children: A Meta-analysis

Alaa Ahmed Abd El Hamid1, Anas Mohamed Askoura1, Diaa Marzouk Abdel Hamed1

  • 1Department of Family Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

The Open Respiratory Medicine Journal
|December 10, 2020
PubMed

Insights

Surgical treatment, specifically adenotonsillectomy, significantly improved quality of life for children with obstructive sleep-disordered breathing (OSDB) compared to non-surgical options. This meta-analysis highlights surgical benefits for OSDB management.

Area of Science:

  • Pediatric Otolaryngology
  • Sleep Medicine
  • Evidence-Based Medicine

Background:

  • Obstructive sleep-disordered breathing (OSDB) encompasses chronic conditions marked by repeated breathing cessations during sleep.
  • OSDB leads to fatigue and daytime sleepiness, significantly impairing daily functioning and quality of life.

Purpose of the Study:

  • To compare the efficacy of surgical versus non-surgical interventions for OSDB in pediatric populations.
  • To conduct a meta-analysis of clinical trials evaluating treatment outcomes for childhood OSDB.

Main Methods:

  • A systematic literature search identified relevant studies and abstracts on surgical and non-surgical OSDB treatments in children.
  • Data extraction focused on risk estimates and 95% confidence intervals from each included study.

Main Results:

  • Surgically treated pediatric patients demonstrated statistically significant improvements in quality of life compared to those receiving non-surgical treatment.
  • Adenotonsillectomy was identified as a key surgical intervention showing positive outcomes.

Conclusions:

  • This meta-analysis indicates superior clinical improvement in the surgical (adenotonsillectomy) group versus the non-surgical group for pediatric OSDB.
  • Surgical intervention positively impacts disease-specific quality of life and healthcare utilization in children with OSDB.
Abstract

Keywords:
ChildrenMeta-analysisOSDBQuality of lifeSurgicalSystematic review

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