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Generation of Discriminative Human Monoclonal Antibodies from Rare Antigen-specific B Cells Circulating in Blood
Published on: February 6, 2018
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Monoclonal Antibodies to Human Cell Surface Antigens
Hannes Stockinger1, Otto Majdic1, Walter Knapp1
1Institute of Immunology, University of Vienna, Vienna, Austria.
Current Protocols in Immunology
|December 10, 2020
Summary
This resource provides a comprehensive list of cluster of differentiation (CD) markers for over 300 leukocyte surface molecules. It is approved by the International Union of Immunological Societies (IUIS) nomenclature committee.
Area of Science:
- Immunology
- Cell Biology
- Biochemistry
Background:
- Leukocyte surface molecules play critical roles in cellular functions and immune responses.
- Standardized nomenclature is essential for clear communication in immunology research.
Purpose of the Study:
- To present an updated and approved list of cluster of differentiation (CD) designations.
- To catalog nearly 300 leukocyte surface molecules recognized by the IUIS.
Main Methods:
- Compilation of approved CD designations.
- Review and approval by the IUIS nomenclature committee.
Main Results:
- A comprehensive list of approximately 300 distinct leukocyte surface molecules with their assigned CD designations.
- Official approval of these designations by the IUIS nomenclature committee.
Conclusions:
- The provided appendix serves as a definitive reference for leukocyte surface molecule nomenclature.
- Facilitates consistent and accurate identification of cell surface markers in immunological studies.
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