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Immunobiology of acute graft-versus-host disease
1Transplantation Laboratory, University of Helsinki, Finland.
Abstract:
Acute graft-versus-host disease (aGVHD) remains one of the major obstacles in bone marrow transplantation. The histological changes of aGVHD have been documented thoroughly; much less is known about the inflammatory cell populations causing the reaction. This review focuses on the inflammatory cells isolated from the different target organs during aGVHD.