Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

699
Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by...
699
Adrenergic Agonists: Mixed-Action Agents01:28

Adrenergic Agonists: Mixed-Action Agents

1.2K
Mixed-action adrenergic agonists, like ephedrine and pseudoephedrine, directly and indirectly affect adrenergic receptors. These agents stimulate adrenoceptors and indirectly release stored neurotransmitters, amplifying the adrenergic response.
Ephedrine and pseudoephedrine lack a catecholamine group, making them less susceptible to degradation by metabolic enzymes. They have increased oral bioavailability and lipophilicity, resulting in a longer duration of action. Their response is reduced by...
1.2K
Teratogenicity01:07

Teratogenicity

3.7K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
3.7K
Phase II Reactions: Methylation Reactions01:17

Phase II Reactions: Methylation Reactions

523
Methylation is a phase II biotransformation process involving the attachment of a methyl group to a substrate. Enzymes known as methyltransferases orchestrate this reaction.
The mechanism of methylation unfolds in two stages. The first stage sees a methyltransferase enzyme facilitating the transfer of a methyl group from S-adenosylmethionine (SAM) to the substrate, forming S-adenosylhomocysteine (SAH). The second stage involves further metabolism of SAH into homocysteine, which can be recycled...
523
Stimulants01:29

Stimulants

645
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
645
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

571
CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
571

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A systematic review examining the association between parity and gravidity & hypertension and blood pressure.

NPJ cardiovascular health·2026
Same author

Impact of Real-Time Continuous Glucose Monitoring on Medication Use and Glycemic Control in Type 2 Diabetes Across Therapy Regimens.

Diabetes, metabolic syndrome and obesity : targets and therapy·2026
Same author

Trainee Leadership in Action: The Impact of the Canadian Association of Radiologists Resident and Fellow Section Medical Student Network.

Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes·2026
Same author

Prevention of Maternal Mortality in Canada: A Report on the SOGC National Summit of 2023 with a Call for Urgent Action Across the Country.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC·2026
Same author

From Summit to Strategy: Advancing a National Response to Prevent Maternal Mortality in Canada: Proceedings from the 2024 Summit.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC·2026
Same author

What Ontario's Maternal Death Reviews Reveal About Canada's Missed Opportunities for Preventing Maternal Mortality.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC·2026

Related Experiment Videos

Methamphetamine Use in Pregnancy: A Call for Action.

Lisa E Graves1, Courtney R Green2, Magali Robert3

  • 1Family and Community Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, MI.

Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'Obstetrique Et Gynecologie Du Canada : JOGC
|December 10, 2020
PubMed
Summary

Methamphetamine use in pregnant women is a growing concern in Canada. More research is urgently needed to understand its prevalence and impact on maternal and fetal health.

Keywords:
infantsmethamphetaminepregnancyscreeningsubstance abusetreatment

Related Experiment Videos

Area of Science:

  • Obstetrics and Gynecology
  • Maternal Health
  • Neonatal Health

Background:

  • Substance use during pregnancy is a significant public health issue in Canada.
  • Increasing rates of substance use among women of childbearing age necessitate further investigation.
  • Maternity care providers are increasingly encountering pregnant patients using methamphetamine.

Purpose of the Study:

  • To address the gap in knowledge regarding methamphetamine use during pregnancy.
  • To provide evidence-based recommendations for the management and treatment of pregnant methamphetamine users.
  • To improve health outcomes for pregnant women and their infants.

Main Methods:

  • This study synthesizes existing literature and clinical observations.
  • It identifies current gaps in understanding methamphetamine's prevalence and impact.
  • It highlights the need for clinical practice guidelines.

Main Results:

  • The prevalence and specific impacts of methamphetamine use during pregnancy are not well-documented.
  • Maternity care providers require evidence-based guidance for patient management.
  • There is an urgent need for research to inform treatment strategies.

Conclusions:

  • Urgent research is required to understand the effects of methamphetamine on pregnancy.
  • Evidence-based guidelines are essential for healthcare providers managing these cases.
  • Addressing this knowledge gap is critical for improving maternal and infant health outcomes.