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Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors

Guixing Ma1, Sanshan Wang2, Kebin Wu1

  • 1Department of Biology, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research and Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen 518055, Guangdong, China.

Bioorganic & Medicinal Chemistry
|December 10, 2020
PubMed

Keywords:
Antibiotic resistanceD-captopril derivativesDrug discoveryMetallo-β-lactamase inhibitorsMetallo-β-lactamases (MBLs)Thiol compounds

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