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Updated: Nov 26, 2025

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Challenging anticoagulation cases: A case of acute pulmonary embolism in a patient with chronic thrombocytopenia
Kerstin de Wit1, Lori-Ann Linkins1
1Department of Medicine, McMaster University, Hamilton, Canada.
Abstract:
We present a case of acute pulmonary embolism in a patient with myelofibrosis and thrombocytopenia. The patient had a history of portal vein thrombosis and had taken warfarin for the past six years. At the time of his pulmonary embolism diagnosis, his INR was 1.5 and platelet count 58 × 109/L. This article discusses how to balance the risk of thrombosis against the risk of bleeding, and reviews the options for pulmonary embolism treatment including transition to low-molecular-weight heparin, direct oral anticoagulants and/or inferior vena cava filters.
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