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Updated: Nov 26, 2025

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
SUBOPTIMAL MODULATION OF RADIATION DOSE IN THE COMPUTED TOMOGRAPHY COMPONENT OF WHOLE-BODY POSITRON EMISSION
Yusuke Inoue1, Mizuho Adachi1, Hirokazu Shimizu1
1Department of Diagnostic Radiology, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, Japan.
Abstract:
Radiation exposure in computed tomography (CT) is automatically modulated by automatic exposure control (AEC) mainly based on scout images. To simulate the whole-body positron emission tomography/CT, CT images of a phantom were obtained using the posteroanterior scout image alone (PA scout) or the posteroanterior and lateral images (PA + Lat scout). Old and new versions of the AEC software were compared. Using the old version of the software and the PA scout, a markedly high dose at the top of the head was observed, which varied depending on the position of the phantom. This issue was resolved in the new version of the software. Radiation dose in the shoulder region was much higher using the PA scout than using the PA + Lat scout, even with the new version of the software. AEC may cause unreasonably high radiation exposure locally, and the appropriateness of the dose modulation pattern should be examined at each facility.
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