Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Flower-like Silver Bismuth Sulfide/Carbon Nanosphere Nanocomposite for Sensitive Electrochemical Tumor Marker Sensing.

ACS measurement science au·2026

Same author

Laser-scribed Graphene Electrodes Functionalized with Nafion/Fe<sub>3</sub>O<sub>4</sub> Nanohybrids for the Ultrasensitive Detection of Neurotoxin Drug Clioquinol.

ACS omega·2022

Same author

Tungsten Disulfide Nanotube-Modified Conductive Paper-Based Chemiresistive Sensor for the Application in Volatile Organic Compounds' Detection.

Sensors (Basel, Switzerland)·2021

Same author

A Graphene-PEDOT:PSS Modified Paper-Based Aptasensor for Electrochemical Impedance Spectroscopy Detection of Tumor Marker.

Sensors (Basel, Switzerland)·2020

Same author

A Real-Time Thermal Self-Elimination Method for Static Mode Operated Freestanding Piezoresistive Microcantilever-Based Biosensors.

Biosensors·2018

Search research articles

Related Experiment Video

Updated: Nov 26, 2025

Microfabricated Post-Array-Detectors mPADs: an Approach to Isolate Mechanical Forces

Microfabricated Post-Array-Detectors mPADs: an Approach to Isolate Mechanical Forces

Published on: October 1, 2007

Portable Real-Time Detection of Pb(II) Using a CMOS MEMS-Based Nanomechanical Sensing Array Modified with PEDOT:PSS.

Yi-Kuang Yen^1,2, Chao-Yu Lai¹

¹Department of Mechanical Engineering, National Taipei University of Technology, Taipei 106, Taiwan.

Nanomaterials (Basel, Switzerland)

|December 11, 2020

Summary

This study introduces a new nanomechanical sensor for detecting lead (Pb²⁺) ions in water. The device offers a sensitive, portable, and cost-effective method for on-site water quality monitoring.

Keywords:

CMOS MEMS conductive polymer lead ion detection nanomechanical sensor

More Related Videos

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors

Published on: November 20, 2013

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

Related Experiment Videos

Last Updated: Nov 26, 2025

Microfabricated Post-Array-Detectors mPADs: an Approach to Isolate Mechanical Forces

Microfabricated Post-Array-Detectors mPADs: an Approach to Isolate Mechanical Forces

Published on: October 1, 2007

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors

Published on: November 20, 2013

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

Area of Science:

Materials Science
Environmental Science
Sensor Technology

Background:

Lead (Pb²⁺) ion detection is crucial for water quality monitoring due to health risks.
Existing methods may lack portability or cost-effectiveness for widespread use.

Purpose of the Study:

To develop a nanomechanical sensor for sensitive and specific Pb²⁺ detection.
To utilize CMOS MEMS technology for a miniaturized and mass-producible sensor platform.

Main Methods:

Employing complementary metal-oxide-semiconductor microelectromechanical system (CMOS MEMS)-based piezoresistive microcantilevers.
Coating microcantilevers with PEDOT:PSS sensing layers that oxidize upon reaction with Pb²⁺.
Measuring surface stress changes via microcantilever bending and relative resistance changes.

Main Results:

The sensor demonstrated sensitivity to Pb²⁺ in a linear range of 0.01-1000 ppm.
Achieved a limit of detection of 5 ppb for Pb²⁺ ions.
Exhibited specificity to Pb²⁺, required small sample volumes, and was easy to operate.

Conclusions:

The developed nanomechanical sensor is a sensitive, cost-effective, and portable tool.
This technology is suitable for on-site water quality measurement and pollution detection.
CMOS MEMS integration enables mass production and miniaturization for practical applications.