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Flaxseed oil stimulates gynecomastia
Tsuneo Takenaka1, Mayuko Nagano2, Koji Yamashita2
1Department of Medicine and Surgery, Kokusai Iryo Fukushi Daigaku Daigakuin-Tokyo Aoyama Campus, Minato-ku, Tokyo, Japan takenaka@iuhw.ac.jp.
Abstract:
Flaxseed oil contains lignans, which exhibit anti-inflammatory and antiatherogenic activities. A 70-year-old male patient presented to our office due to hyperlipidaemia and started to take a tablespoon of flaxseed oil daily. Three months later, he reported left breast swelling and pain. Although the echogram revealed a tumour in the left mammary gland, the breast biopsy was compatible with gynecomastia, showing ductal hyperplasia without evidence of malignancy. His breast epithelia were oestrogen receptor-positive. Potential role of phytoestrogens was discussed.
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