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An update on COVID-19 pandemic: the epidemiology, pathogenesis, prevention and treatment strategies

Hin Fung Tsang1, Lawrence Wing Chi Chan1, William Chi Shing Cho2

  • 1Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hong Kong Special Administrative Region.

Expert Review of Anti-Infective Therapy
|December 11, 2020
PubMed

Insights

The COVID-19 pandemic remains a global challenge with no specific antiviral treatments. Public health measures and exploring repurposed drugs are key to managing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Virology

Background:

  • Coronavirus Disease-2019 (COVID-19) transmission is ongoing, with millions of confirmed cases and deaths reported globally.
  • No specific antiviral treatments are currently available for COVID-19, and treatment guidelines vary internationally.

Purpose of the Study:

  • To summarize current knowledge on the COVID-19 pandemic.
  • To discuss the epidemiology, pathogenesis, prevention, and treatment options for SARS-CoV-2.

Main Methods:

  • Literature review and synthesis of existing data on COVID-19.
  • Discussion of various therapeutic strategies, including combination therapies and drug repurposing.

Main Results:

  • The COVID-19 pandemic situation remains unpredictable.
  • Combination therapies show promise, and repurposing FDA-approved drugs is a potential treatment avenue.

Conclusions:

  • Effective prevention relies on robust protection, precautions, and public health measures.
  • Further research into vaccines and specific antiviral drugs is crucial for controlling the pandemic.
Abstract

Keywords:
COVID-19COVID-19 managementCOVID-19 treatmentSARS-CoV-2coronavirus Disease-2019novel coronavirussevere acute respiratory syndrome coronavirus 2

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