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Risk Factors for Progression From Gestational Diabetes to Postpartum Type 2 Diabetes: A Review

Angela M Bengtson1, Sebastian Z Ramos2, David A Savitz1,2

  • 1Department of Epidemiology, Brown University School of Public Health.

Clinical Obstetrics and Gynecology
|December 11, 2020
PubMed

Gestational diabetes mellitus (GDM) complicates 6% to 8% of pregnancies and up to 50% of women with GDM progress to type 2 diabetes mellitus (DM) within 5 years postpartum. Clinicians have little guidance on which women are most at risk for DM progression or when evidence-based prevention strategies should be implemented in a woman's lifecycle. To help address this gap, the authors review identifiable determinants of progression from GDM to DM across the perinatal period, considering prepregnancy, pregnancy, and postpartum periods. The authors categorize evidence by pathways of risk including genetic, metabolic, and behavioral factors that influence progression to DM among women with GDM.

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