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Updated: Nov 26, 2025

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
Published on: March 5, 2022
Polycystic Ovarian Syndrome Genetics and Epigenetics
Joshua C Combs1,2, Micah J Hill1,2, Alan H Decherney1
1Eunice Kennedy Shriver National Institute of Child Health and Human Development.
Abstract:
Polycystic ovarian syndrome and its associated endocrine abnormalities comprise one of the most common metabolic spectrum disorders within the human race. Because of the variance in phenotypic expression among individuals and within family lineages, attention has been turned to genetic and epigenetic changes in which the root cause of the disorder may lie. Further understanding of DNA/histone methylation and microRNA patterns may help to improve the accuracy of diagnosis and lead to future treatment options.
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