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Updated: Nov 26, 2025

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
Published on: April 21, 2022
Retinal vascular occlusions
Ingrid U Scott1, Peter A Campochiaro2, Nancy J Newman3
1Department of Ophthalmology and Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA.
Abstract:
Acute retinal vascular occlusions are common causes of visual impairment. Although both retinal artery occlusions and retinal vein occlusions are associated with increased age and cardiovascular risk factors, their pathophysiology, systemic implications, and management differ substantially. Acute management of retinal artery occlusions involves a multidisciplinary approach including neurologists with stroke expertise, whereas treatment of retinal vein occlusions is provided by ophthalmologists. Optimisation of systemic risk factors by patients' primary care providers is an important component of the management of these two disorders.

