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Persistent hiccup: A rare presentation of COVID-19
Nader Bakheet1, Rabab Fouad1, Abdel Meguid Kassem1
1Tropical Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Persistent hiccups can be an unusual symptom of COVID-19. This case report highlights a patient with coronavirus disease (COVID-19) who experienced prolonged hiccups along with fever and sore throat.
Area of Science:
- Internal Medicine
- Infectious Diseases
- Pulmonology
Background:
- Hiccups are involuntary diaphragmatic contractions, classified as acute (<48 hours) or persistent (>48 hours).
- Coronavirus disease (COVID-19) presents with diverse symptoms, including atypical manifestations beyond the typical fever and cough.
Observation:
- A 48-year-old male presented with a seven-day history of persistent hiccups, fever, and sore throat.
- Initial examination revealed gaseous abdominal distension, with laboratory tests showing elevated inflammatory markers (C-reactive protein, ferritin, lactate dehydrogenase).
Findings:
- Chest CT scans indicated bilateral ground-glass opacities and a crazy-paving pattern, suggestive of viral pneumonia.
- The patient tested positive for COVID-19, and treatment with hydroxychloroquine, oseltamivir, and baclofen led to improvement in hiccups.
Implications:
- This case underscores the importance of considering COVID-19 in patients presenting with atypical symptoms like persistent hiccups.
- Healthcare providers should maintain a high index of suspicion for coronavirus disease (COVID-19) even with unusual clinical presentations.
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