Low skeletal bone mineral density as a potential aetiological factor towards idiopathic condylar resorption

The aim of this study was to investigate the contributing factor of impaired skeletal quality in the pathogenesis of idiopathic condylar resorption (ICR). One hundred and twenty-six patients with MRI-confirmed ICR and 596 patients with disc displacement (DD) without a diminished condyle, of both sexes, were included. Dental examinations and retrospective surveys regarding temporomandibular joint symptoms and progression of maxillofacial deformities were conducted. Skeletal bone mineral density (BMD) was measured by dual energy X-ray absorptiometry (DXA) and converted to T-scores and Z-scores. Results showed that ICR patients had a smaller overbite (1.56±3.3 vs 3.05±2.0mm), larger overjet (4.9±2.4 vs 3.5±1.9mm), larger range of mouth opening (36.5±6.7 vs 33.6±7.1mm), and higher rates of anterior open bite and mandibular retrusion compared to DD patients (all P<0.001). ICR was associated with an increased probability of low skeletal BMD at chronological age in females (P=0.020) but not in males (P=0.095). This study indicates that reduced BMD may predispose females to an exacerbated condylar resorption process in addition to increased joint loading initiated from DD.