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Updated: Nov 26, 2025
Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
Published on: May 10, 2021
Addressing the contralateral neck for ipsilateral disease recurrence in oral cavity cancers
Hitesh Rajendra Singhavi1, Sudhir Nair2, Manish Mair3
1Department of Head and Neck Surgical Oncology, TMH, Tata Memorial Centre, Mumbai, India; Homi Bhabha National Institute, Mumbai, India; Consultant Head & Neck Surgeon, Fortis Hospital, Mulund, Mumbai, India.
Background:
Evidence for performing contralateral neck dissection (CND) of recurrent oral cavity squamous cell cancers (OCSCC) is lacking.
Material And Methods:
This is a retrospective study of 78 consecutive OCSCC having ipsilateral recurrence recorded over five years. We screened 1658 OCSCC patients and selected those patients who underwent CND as part of treatment for ipsilateral recurrence.
Results:
The median disease-free interval was 32 months. Incidence of contralateral nodal metastasis (CNM) in recurrent OCSCC was 23.1% and of which 14% were occult. The factor significantly influencing CNM was the depth of invasion (DOI) > 10 mm (p < 0.01). In our study, imaging had suboptimal PPV (33%) while it had high NPV (88%) in diagnosing nodal metastasis in recurrent OCSCC.
Conclusion:
DOI is the most important factor predicting CNM in case of ipsilateral primary recurrence. PET-CECT has a high NPV and contralateral neck should be addressed in case of tumours with higher DOI.
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