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Published on: December 11, 2017
Contemporary trends in surgical rheumatic valve disease in a Caribbean nation
Nicola Pradegan1, Juan R León-Wyss1, José R Iribarren1
1CEDIMAT Cardiovascular Center, Santo Domingo, Dominican Republic.
Insights
Rheumatic heart disease (RHD) surgery is increasing in the Dominican Republic, predominantly affecting younger patients with mitral valve issues. Prosthetic replacement is the main procedure, highlighting a growing public health concern.
Area of Science:
- Cardiovascular Surgery
- Public Health
- Rheumatology
Background:
- Rheumatic heart disease (RHD) poses a significant public health challenge in the Caribbean.
- Advanced RHD often necessitates early surgical intervention.
Purpose of the Study:
- To determine the burden of RHD among patients undergoing valve surgery in the Dominican Republic.
- To identify the types of procedures performed for RHD in the study population.
Main Methods:
- Retrospective analysis of demographic, clinical, and procedural data from January 2014 to December 2018.
- Inclusion of all patients undergoing valvular surgery across 7 cardiovascular surgical centers.
- Correlation coefficients used to assess yearly trends in RHD procedures.
Main Results:
- Out of 1626 valvular surgeries, 733 (45%) were for RHD.
- Mitral valve involvement was most common (63%), followed by combined mitral/aortic (19%).
- An upward trend in RHD valvular surgery was observed (mean annual increment of 50%, P=0.01), affecting a younger population (mean age 50 ± 11 years).
Conclusions:
- Surgical rates for RHD in the Dominican Republic have increased over the past five years.
- The study highlights a trend of RHD affecting a relatively young population, with mitral valve disease being predominant.
- Findings can inform policy for cost-effective RHD initiatives in the region.
Background:
Clinical practice suggests that rheumatic heart disease (RHD) represents a significant public health challenge in the Caribbean region where advanced disease appears early often leading to surgical intervention. We aimed to determine the burden of RHD and type of procedure among patients undergoing valve surgery in the Dominican Republic (DR).
Methods:
Demographic, clinical and procedural data of all subjects intervened between January 2014 and December 2018 were obtained including valve disorder, anatomic location and type of surgery. Correlation coefficients were used to assess yearly trends of RHD among the 7 cardiovascular surgical centers in the country.
Results:
Of 1626 valvular surgeries performed, 733 (45%) corresponded to RHD; 55% female patients, age 50 ± 11 (6-72) years; involving mitral 458 (63%); mitral + aortic 139 (19%); aortic 105 (14%); mitral + tricuspid 31 (4%); 95% prosthetic replacement and 5% mitral/tricuspid repairs. Mean proportion of RHD valve procedures per center for the study period was 53 ± 34%. Age-adjusted analysis showed an overall upwards trend in RHD valvular surgery (mean annual increment of 50 ± 40%, P = 0.01).
Conclusions:
Despite inter-center variability, rates of surgical RHD in the DR increased during the last 5 years affecting a relatively young population. Mitral involvement was the predominant lesion and prosthetic replacement the leading procedure. These data may guide local and regional institutions and policy makers towards the implementation of cost-effective initiatives against RHD.
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