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On selecting the critical boundary functions in group-sequential trials with two time-to-event outcomes

Toshimitsu Hamasaki1, H M James Hung2, Chin-Fu Hsiao3

  • 1The Biostatistics Center and the Innovations in Design, Education, and Analysis Committee (IDEA), the George Washington University, USA; Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, the George Washington University, USA.

Contemporary Clinical Trials
|December 14, 2020
PubMed

Keywords:
Bonferroni-Holm procedureConjunctive powerDisjunctive powerFixed-sequence procedureLogrank testO'Brien-Fleming-type boundary functionPocock-type boundary function

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