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Salmonella osteomyelitis after internal fixation of fracture

I Caspi1, E Ezra, E Lin

  • 1Department of Orthopaedic Surgery B, Chaim Sheba Medical Center, Tel-Hashomer, Israel.

Orthopaedic Review
|March 1, 1986
PubMed

Insights

Salmonella enteritidis osteomyelitis in a surgically treated femur resisted antibiotic treatment. Eradicating the infection required removing the internal fixation plate, highlighting the role of foreign bodies in persistent bone infections.

Area of Science:

  • Orthopedic Surgery
  • Infectious Diseases
  • Microbiology

Background:

  • Osteomyelitis is a serious bone infection.
  • Surgical interventions for bone fractures often involve internal fixation devices.
  • Foreign bodies can complicate infection management.

Observation:

  • A patient presented with acute Salmonella group D (Salmonella enteritidis) osteomyelitis in a previously operated femur.
  • The infection was localized around an internal fixation plate.
  • The patient did not respond to chloramphenicol or aztreonam therapy.

Findings:

  • The persistent Salmonella enteritidis infection was refractory to standard antibiotic regimens.
  • Complete eradication of the local infection was achieved only after the removal of the internal fixation plate.
  • The presence of the foreign body (internal fixation plate) was a critical factor in the treatment failure.

Implications:

  • This case underscores the importance of considering foreign body involvement in refractory osteomyelitis.
  • Removal of orthopedic implants may be necessary for successful treatment of deep-seated bone infections.
  • Effective management of Salmonella enteritidis osteomyelitis in the context of orthopedic hardware requires a multidisciplinary approach.

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