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Related Experiment Video

Updated: Nov 26, 2025

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Pulmonary sequestration: What the radiologist should know.

Michela Gabelloni1, Lorenzo Faggioni1, Sandra Accogli1

  • 1Diagnostic and Interventional Radiology, Department of Translational Research, University of Pisa, Via Roma, 67, 56126 Pisa, Italy.

Clinical Imaging
|December 14, 2020
PubMed
Summary

Pulmonary sequestration is a congenital lung anomaly where lung tissue lacks normal airways and receives blood from systemic vessels. Imaging, particularly multidetector computed tomography, is crucial for diagnosing and managing this condition.

Keywords:
Diagnostic imagingExtralobar pulmonary sequestrationIntralobar pulmonary sequestrationTherapeutic embolization

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Area of Science:

  • Pulmonology
  • Pediatric Radiology
  • Congenital Anomalies

Background:

  • Pulmonary sequestration is a rare congenital lung malformation characterized by non-aerated lung tissue with systemic arterial supply.
  • It is classified as intralobar or extralobar based on pleural investment.
  • Accurate diagnosis is essential for managing potential complications.

Purpose of the Study:

  • To provide an overview of pulmonary sequestration.
  • To describe its pathophysiology, clinical presentation, and imaging findings.
  • To highlight the role of multidetector computed tomography in diagnosis.

Main Methods:

  • Review of existing literature on pulmonary sequestration.
  • Emphasis on imaging characteristics, particularly multidetector computed tomography (MDCT).
  • Discussion of diagnostic approaches and management strategies.

Main Results:

  • Pulmonary sequestration is the second most common congenital lung anomaly, though likely underdiagnosed.
  • Key imaging findings include identification of systemic arterial supply and absence of normal tracheobronchial communication.
  • MDCT offers a comprehensive evaluation of intralobar and extralobar types.

Conclusions:

  • Pulmonary sequestration requires a thorough diagnostic approach, with MDCT being a pivotal tool.
  • Understanding the imaging features is critical for effective clinical management.
  • Early and accurate diagnosis impacts patient outcomes.