Related Experiment Video
Updated: Nov 26, 2025

03:55
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
785
Benign thyroid swelling presenting as Horner's syndrome
Sherin K Shaji1, Jacquline Chan2, Churunal Hari2
1Department of Otolaryngology, Shrewsbury and Telford Hospital NHS Trust, Telford, UK sherin.shaji@nhs.net.
BMJ Case Reports
|December 14, 2020
Summary
Horner's syndrome, a rare neurological condition, can be caused by thyroid swelling compressing the sympathetic chain. This case highlights a benign thyroid nodule as the initial presentation of this rare association.
Area of Science:
- Neurology
- Endocrinology
- Ophthalmology
Background:
- Horner's syndrome results from disrupted sympathetic nerve supply to the face and eye.
- Thyroid swelling is common, but rarely compresses the cervical sympathetic chain.
- Previous associations between thyroid issues and Horner's syndrome are documented.
Observation:
- A 54-year-old man presented with symptoms of Horner's syndrome.
- The patient had a benign thyroid nodule causing pressure on the sympathetic chain.
- This presentation was the first indication of the underlying thyroid swelling.
Findings:
- A benign thyroid nodule can cause Horner's syndrome through direct compression.
- Horner's syndrome can be the initial presenting sign of a benign thyroid swelling.
- This case represents a rare etiological link between thyroid pathology and neurological deficit.
Implications:
- Highlights the importance of considering thyroid pathology in unexplained Horner's syndrome.
- Suggests that benign thyroid nodules can have significant neurological consequences.
- Underscores the need for thorough evaluation of neck masses, even if seemingly benign.
More Related Videos
Related Concept Videos
The Thyroid Gland
6.0K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
6.0K
Synthesis and Regulation of Thyroid Hormones
6.5K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
6.5K
Major Hormones and Their Functions
1.3K
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
1.3K
The Hyoid Bone
3.9K
The hyoid bone is a small U-shaped bone located in the upper neck at the level of the inferior mandible, with its tips pointing posteriorly. It does not directly articulate with any other bone in the body. The hyoid acts as the attachment site for the tongue, the larynx, and the pharynx. It is held in position by a series of small muscles attached from above or below. These muscles help to move the hyoid up/down or forward/back in coordination with movements of the tongue, larynx, and pharynx...
3.9K
Chronic Pharyngitis
8.4K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
8.4K
Functions of Thyroid Hormones
4.5K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
4.5K

