Related Experiment Video
Updated: Nov 26, 2025

Fast and Accurate Exhaled Breath Ammonia Measurement
Published on: June 11, 2014
Ammonia: what adult neurologists need to know
Rick Meijer1,2, Umesh Vivekananda3, Simona Balestrini3,4
1Department of Internal Medicine, Amsterdam University Medical Centers, Location VU University Medical Center, Amsterdam, The Netherlands.
Abstract:
Hyperammonaemia is often encountered in acute neurology and can be the cause of acute or chronic neurological symptoms. Patients with hyperammonaemia may present with seizures or encephalopathy, or may be entirely asymptomatic. The underlying causes are diverse but often straightforward to diagnose, although sometimes require specialist investigations. Haemodialysis or haemo(dia)filtration is the first-line treatment for acute severe hyperammonaemia (of any cause) in an adult. Here we discuss our approach to adult patients with hyperammonaemia identified by a neurologist.
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