Related Experiment Video

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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

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Relation between Hemoconcentration Status and Readmission Plus Mortality Rate Among Iranian Individuals with

Ashkan Yadollahi Farsani1, Mehrbod Vakhshoori2, Asieh Mansouri3

  • 1Heart Failure Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

International Journal of Preventive Medicine
|December 14, 2020
PubMed

Insights

Hemoconcentration (HC) may be a biomarker for heart failure (HF) risk. While not significantly impacting rehospitalization, HC showed a trend towards lower mortality in acute HF patients.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Hemoconcentration (HC) is a potential biomarker for optimizing diuretic therapy in acute heart failure (HF).
  • The association between HC and rehospitalization or mortality in HF patients remains debated.
  • This study investigated the relationship between HC and readmission/mortality rates in Iranian acute HF patients.

Purpose of the Study:

  • To determine the association between hemoconcentration (HC) and rehospitalization and mortality rates in acute heart failure (HF) patients.
  • To evaluate HC as a potential biomarker for risk stratification in HF management.

Main Methods:

  • Prospective cohort study (March 2017-March 2018) using data from the Persian Registry Of cardioVascular diseasE.
  • Included 390 adult patients with acute HF; 69 exhibited hemoconcentration (increased hemoglobin levels during hospitalization).
  • Analyzed the relationship between HC and readmission/mortality using logistic regression and Cox proportional hazard models.

Main Results:

  • The study population (n=390) had a mean age of 70.5 years, with 66.9% males.
  • Patients with HC did not show a significant difference in rehospitalization rates compared to those without HC.
  • Patients with HC exhibited a borderline significant lower likelihood of mortality (HR 0.82, P=0.08).

Conclusions:

  • Hemoconcentration (HC) is marginally associated with reduced 6-month mortality post-acute heart failure (HF).
  • HC may serve as a useful biomarker for risk stratification in HF patients.
  • Further prospective, population-based studies are needed to confirm these findings.
Abstract

Keywords:
Anemiaheart failurehemoglobinshospitalizationpatient admission

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