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Updated: Nov 26, 2025

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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
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A step-by-step guide to trans-axillary transcatheter aortic valve replacement
Morgan T Harloff1, Edward D Percy1, Sameer A Hirji1
1Division of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Annals of Cardiothoracic Surgery
|December 14, 2020
Summary
Transcatheter aortic valve replacement (TAVR) via the axillary artery (TAx) offers a less invasive alternative when transfemoral access is not feasible. This approach bypasses the need for thoracic entry, utilizing familiar surgical techniques.
Area of Science:
- Cardiovascular Interventions
- Minimally Invasive Surgery
- Structural Heart Disease
Background:
- Transcatheter aortic valve replacement (TAVR) is a key treatment for severe aortic stenosis, requiring large-bore catheter access.
- Transfemoral (TF) access is preferred, but alternative routes are necessary for patients with unsuitable iliofemoral vessels.
Discussion:
- Trans-axillary TAVR (TAx-TAVR) provides a peripheral vascular access option, avoiding pericardial or thoracic cavity entry.
- The axillary artery approach utilizes surgical techniques familiar to cardiac surgeons.
- Advancements in TAVR technology are enabling totally percutaneous axillary access.
Key Insights:
- TAx-TAVR is a viable alternative for patients unsuitable for TF access.
- The procedure leverages established surgical familiarity with the axillary artery.
- Evolving TAVR systems facilitate less invasive percutaneous axillary access.
Outlook:
- Further research into patient selection, imaging, and procedural optimization for TAx-TAVR is warranted.
- Contemporary clinical outcomes for TAx-TAVR are being actively examined.
- The increasing adoption of TAx-TAVR reflects its growing importance in TAVR access strategies.
Keywords:
Tax-TAVRTranscatheter aortic valve replacement (TAVR)alternative accesstrans-axillary (TAx) TAVRMore Related Videos
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