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The Trends of Single-Cell Analysis: A Global Study.
Hua Tian1, Haifeng Liu2, Yuanyuan Zhu3
1Department of Orthopedic, Xinyi People's Hospital, Xinyi, China.
Biomed Research International
|December 14, 2020
Summary
Bibliometric analysis reveals rapid growth in single-cell research, with the USA leading in impact. Future single-cell studies are expected to focus on fabrication and in vivo methods.
Area of Science:
- Bibliometrics
- Scientific research impact analysis
- Single-cell analysis
Background:
- Single-cell analysis is a rapidly expanding global research field.
- Understanding its development and future trends is crucial.
Purpose of the Study:
- To conduct a bibliometric analysis and visualization of single-cell research publications from 2000-2019.
- To identify key trends, influential countries, institutions, and research topics.
Main Methods:
- Systematic literature search of Web of Science, Scopus, and PubMed databases.
- Bibliometric data compilation including authors, countries, and affiliations.
- Analysis using GraphPad Prism and VOSviewer for bibliographic coupling, coauthorship, cocitation, and co-occurrence.
Main Results:
- 4,071 studies analyzed, showing a substantial increase in publications over time.
- USA leads in impact (H-index, citations); Israel has highest average citations per publication.
- Analytical Chemistry journal and University of Stanford are most prominent; Macosko et al. (2015) is the most cited study. Common topics include mechanistic, in vitro, in vivo, and fabrication studies.
Conclusions:
- Single-cell analysis is a burgeoning scientific area with increasing publication volume.
- Future research is anticipated to emphasize fabrication and in vivo single-cell studies.
