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Related Concept Videos

Brain Imaging01:14

Brain Imaging

495
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
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Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Related Experiment Video

Updated: Nov 26, 2025

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging
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Structural and Functional Imaging in Glioma Management.

Bledi C Brahimaj1, Ryan B Kochanski1, John J Pearce1

  • 1Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois.

Neurosurgery
|December 14, 2020
PubMed
Summary

Advanced imaging techniques improve glioma surgery by precisely mapping critical brain areas. Utilizing multiple modalities aids in surgical planning, enhancing tumor resection and patient outcomes.

Keywords:
Diffusion tensor imagingFunctional MRIGliomaImagingLow-grade gliomaMagnetoencephalographyStimulated Raman microscopyTranscranial magnetic stimulation

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Area of Science:

  • Neurosurgery
  • Neuroradiology
  • Medical Imaging

Background:

  • Maximal safe resection is crucial for glioma patient survival.
  • Traditional contrast-enhanced MRI has limitations in defining eloquent areas.
  • Preoperative imaging is vital for identifying functional brain regions relative to gliomas.

Purpose of the Study:

  • To review advanced imaging modalities for glioma surgery.
  • To detail the technology, clinical use, and limitations of each modality.
  • To emphasize the role of multimodal imaging in surgical planning.

Main Methods:

  • Review of functional MRI (fMRI) for motor and language mapping.
  • Examination of magnetoencephalography (MEG) and transcranial magnetic stimulation (TMS) for cortical localization.
  • Discussion of diffusion tensor imaging (DTI) for white matter tract assessment.
  • Highlighting stimulated Raman spectroscopy (SRS) for intraoperative diagnosis.

Main Results:

  • fMRI effectively identifies hemispheric dominance and functional areas.
  • MEG and TMS offer nuanced localization of eloquent cortex.
  • DTI delineates critical white matter pathways.
  • SRS provides real-time tissue diagnosis during surgery.

Conclusions:

  • Multimodal imaging enhances the understanding of functional anatomy affected by gliomas.
  • Integrating various techniques optimizes surgical planning and patient counseling.
  • Advanced imaging contributes to maximal safe resection and improved patient outcomes.