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Related Experiment Video

Updated: Nov 26, 2025

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
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Published on: August 8, 2025

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Tourniquet use for knee replacement surgery.

Imran Ahmed1, Amit Chawla1, Martin Underwood1

  • 1Warwick Clinical Trials Unit, University of Warwick, Coventry, UK.

The Cochrane Database of Systematic Reviews
|December 14, 2020
PubMed
Summary
This summary is machine-generated.

Tourniquet use in total knee replacement surgery likely increases postoperative pain and serious adverse events, with no clear benefits for function or success. Patients should be informed of potential risks before the procedure.

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Area of Science:

  • Orthopedic Surgery
  • Medical Device Efficacy
  • Patient Safety

Background:

  • Surgeons often use tourniquets during total knee replacement (TKR) to create a bloodless surgical field.
  • Tourniquet use may increase the risk of postoperative pain and complications.

Purpose of the Study:

  • To evaluate the benefits and harms of using tourniquets in knee replacement surgery.

Main Methods:

  • Systematic review of randomized controlled trials (RCTs) and non-randomized studies.
  • Searched major databases (MEDLINE, Embase, CENTRAL) and trial registries.
  • Assessed outcomes including pain, function, adverse events, and implant survival using GRADE criteria.

Main Results:

  • Tourniquet use was associated with higher postoperative pain (moderate certainty evidence).
  • Risk of serious adverse events was probably higher with tourniquet use (moderate certainty evidence).
  • No significant differences in function, treatment success, or quality of life were observed.

Conclusions:

  • Tourniquet use in TKR likely increases pain and serious adverse events without clear clinical benefits.
  • Further research is needed on cognitive function and implant survival.
  • Informed patient consent regarding potential risks is crucial if tourniquets are used.