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Recent research in organization and expression of immunoglobulin V region genes
1Department of Immunology, AFRC Institute of Animal Physiology and Genetics Research, Babraham, Cambridge, U.K.
Abstract:
The first Jacques Monod Conference was held in Roscoff, Brittany on 1-5 June 1987 and dealt with the topic of 'Selection of Lymphocyte Repertoires' (organizers F. W. Alt, Columbia University, New York. P.-A. Cazenave, Institut Pasteur, Paris and A. Coutinho, Institut Pasteur, Paris). Much of the meeting was concerned with the recent developments in immunoglobulin and T-cell receptor V region organization and expression. This review is based on the contributions and discussions on Ig V genes, in particular their organization, rearrangements, allelic exclusion and somatic mutation. (Names without references indicate the conference speaker on that topic.)
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