Degradation mechanism of Ibuprofen via a forward osmosis membrane bioreactor
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Updated: Nov 26, 2025

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
Published on: November 30, 2022
Meichen Yao1, Liang Duan1, Yonghui Song1
1State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China; State Environmental Protection Key Laboratory of Estuarine and Coastal Environment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China.
Abstract:
Ibuprofen (IBU) is a non-steroidal drug that is classified as a trace organic compound (TrOC). A forward osmosis membrane bioreactor (FOMBR) has traditionally been a favored technology for wastewater treatment. In this study, the IBU degradation mechanism was clarified using an FOMBR. The results indicated that the average removal efficiencies of contaminants were greater than 96.32%. The ultra-performance liquid chromatography time-of-flight mass spectrometry (UPLC-TOF-MS) results demonstrated that there were 10 intermediates and 5 possible pathways during the IBU degradation. Decarboxylation and hydroxylation may be the primary pathways of IBU degradation. The microbial results illustrated that Proteobacteria was dominant and of utmost importance in the degradation process. Thauera and Azoarcus were the dominant genera that participated in contaminant degradation.
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