Penile squamous cell carcinoma following childhood hypospadias repair

Alexander Ngoo1, Jodi Hirst2, David Wong3

  • 1Urology, Mater Hospital Brisbane, Brisbane, Queensland, Australia ngoo_3@hotmail.com.

BMJ Case Reports
|December 15, 2020
PubMed

Insights

A man with a history of hypospadias repair developed penile squamous cell carcinoma. Surgical excision was successful, with no recurrence observed at 10 months, highlighting effective treatment for this rare condition.

Area of Science:

  • Urology
  • Oncology
  • Pathology

Background:

  • A 46-year-old male patient with a history of proximal hypospadias repair presented with recurrent lower urinary tract infections and obstructive voiding symptoms.
  • These symptoms suggested a potential complication or sequela related to the prior surgical intervention.

Observation:

  • A mass was identified in the distal urethra during diagnostic evaluation.
  • Biopsy confirmed the mass to be penile squamous cell carcinoma.

Findings:

  • The penile squamous cell carcinoma was successfully excised en bloc.
  • Post-operative follow-up at 10 months showed no evidence of local or regional recurrence.

Implications:

  • This case highlights a rare presentation of penile cancer in the context of hypospadias repair.
  • Successful surgical management offers a positive prognosis for similar cases.
  • Further research may explore long-term outcomes and risk factors in patients with a history of hypospadias surgery.